Vitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis. Vitamin K prophylaxis for prevention of vitamin K deficiency bleeding: a systematic review. Sankar MJ, Chandrasekaran A, Kumar P, et al. National Institutes of Health's Office of Dietary Supplements. A multivitamin with vitamin K may be suggested in conjunction with orlistat. It works by reducing fat absorption, which could, in turn, reduce fat-soluble vitamin absorption. Orlistat: Orlistat is a medication available both as an over-the-counter (OTC) and prescription product for weight loss.They may also reduce vitamin K levels, particularly if taken for several years. They prevent the reabsorption of bile acids, ultimately reducing cholesterol levels.
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